lab news

Here are some of the latest happenings from the Lyon Group. Check out Dr. Lyon’s LinkedIn page for other updates and commentary.

2/26: New paper published in Nanoscale Horizons! The Invited Focus Article “Nanoscale Opportunities in Extracellular Matrix Mimicry” provided us with the opportunity to dive into various aspects of the ECM, the mimicry of which holds promise in transforming regenerative medicine. There is lots of stuff happening at the nanoscale that is difficult to replicate, especially in the context of all the other design requirements that go into functional biomaterials.

12/25: New paper published in Advanced Materials! In the manuscript "Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self-Assembly within Highly Crowded Microgel Pastes", we describe new materials that recapitulate some unique aspects of extracellular matrix. Our lab is actively exploring these structures as a possible new platform for tissue engineering.

12/25: New paper published in Advanced Materials! In the manuscript “Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self-Assembly within Highly Crowded Microgel Pastes“, we describe new materials that recapitulate some unique aspects of extracellular matrix. Our lab is actively exploring these structures as a possible new platform for tissue engineering.

12/25: Another successful microgel symposium! This time, we were in Hawaii for Pacifichem 2025. Looking forward to the next grand convergence of all things microgel…more info on the attendees here.

11/25: Under the leadership of Professor Kamaljit Kaur, we have launched the new Center for Targeted Drug Delivery at Chapman. I am really looking forward to seeing great things emerge from these collaborations.

5/25: New paper PNAS! This is work largely driven by the folks over at Sanguina – “Real-world implementation of a noninvasive, AI-augmented, anemia-screening smartphone app and personalization for hemoglobin level self-monitoring” describes the massive deployment of a mobile app for anemia management, and the actionable healthcare decisions that emerge from that massive dataset.

4/24: New paper Science Translational Medicine! This is work largely driven by Ashley Brown’s lab at NCSU – “Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma” is the culmination of year’s of research into the efficacy, function, and fate of our novel platelet-mimetic microgels. Coolest observation in my opinion? Microgels are soft enough to be eliminated in the urine! This is a real game changer in the world of IV-administered biotechnologies.